EN PL
REVIEW PAPER
Erythema nodosum – review of the literature
 
More details
Hide details
 
Submission date: 2016-03-13
 
 
Final revision date: 2016-04-13
 
 
Acceptance date: 2016-04-26
 
 
Online publication date: 2016-06-03
 
 
Publication date: 2016-04-30
 
 
Reumatologia 2016;54(2):79-82
 
KEYWORDS
TOPICS
ABSTRACT
Erythema nodosum is the most common form of panniculitis. It may have many aetiological factors. Erythema nodosum occurs three to five times more often in female patients. It appears as erythematous painful rounded nodules, located most often on the anterior surface of the lower extremities, and may be accompanied by systemic symptoms such as fever, malaise and arthralgia. During diagnosis, oncological vigilance should be maintained, because erythema nodosum may be a paraneoplastic symptom. It requires an interdisciplinary approach and exclusion of many underlying causes.
 
REFERENCES (25)
1.
Schwartz RA, Nervi SJ. Erythema nodosum: a sign of systemic disease. Am Fam Physician 2007; 75: 695-700.
 
2.
Blake T, Manahan M, Rodins K. Erythema nodosum – a review of an uncommon panniculitis. Dermatol Online J 2014; 20: 22376.
 
3.
Cowan JT, Graham MG. Evaluating the clinical significance of erythema nodosum. Patient Care 2005; 56-58.
 
4.
Acosta KA, Haver MC, Kelly B. Etiology and therapeutic management of erythema nodosum during pregnancy: an update. Am J Clin Dermatol 2013; 14: 215-220.
 
5.
Requena L, Sánchez YE. Erythema nodosum. Semin Cutan Med Surg 2007; 26: 114-122.
 
6.
Sokolik R, Wiland P. Rumień guzowaty. In: Reumatologia. Wielka interna. Puszczewicz M (ed.). Medical Tribune Polska, Warszawa 2010; 226-230.
 
7.
Francès C, Boisnic S, Blétry O, et al. Cutaneous manifestations of Takayasu arteritis. A retrospective study of 80 cases. Dermatologica 1990; 181: 266-272.
 
8.
Pascual-López M, Hernández-Núńez A, Aragüés-Montańés M, et al. Takayasu’s disease with cutaneous involvement. Dermatology 2004; 208: 10-15.
 
9.
Gupta M, Singh K., Lehl SS, Bhalla M. Recurrent erythema nodosum: a red flag sign of hidden systemic vasculitis. BMJ Case Rep 2013; 2013: 10.1136/bcr-2013-009507.
 
10.
Misago N, Tada Y, Koarada S, Narisawa Y. Erythema nodosum-like lesions in Behçet’s disease: a clinicopathological study of 26 cases. Acta Derm Venereol 2012; 92: 681-686.
 
11.
Cebeci F, Onsun N, Ulusal HA, Inan B. The relationship between deep vein thrombosis and erythema nodosum in male patients with Behçet’s disease. Eur Rev Med Pharmacol Sci.2014; 18: 3145-3148.
 
12.
Kwiatkowska B, Przygodzka M, Filipowicz-Sosnowska A. Objawy reumatyczne w chorobach nowotworowych. J Oncol 2006; 56: 693-699.
 
13.
Babamahmoodi F, Babamahmoodi A, Barani H, Delavarian L. Simultaneous occurrence of erythema nodosum in monozygotic twin sisters. Case Rep Med 2012; 2012: 109427.
 
14.
Chen S, Chen J, Chen L, et al. Mycobacterium tuberculosis infection is associated with the development of erythema nodosum and nodular vasculitis. PLoS One 2013; 8(5): e62653.
 
15.
Grzelewska-Rzymowska I. Sarkoidoza – choroba ogólnoustrojowa. Alergia 2012; 2: 23-31.
 
16.
McDougal KE, Fallin MD, Moller D, et al.; and the ACCESS Research Group, Variation in the lymphotoxin-/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis. J Invest Dermatol 2009; 129: 1921-1926.
 
17.
Costabel U, Guzman J, Drent M. Diagnostic approach to sarcoidosis. Eur Respir Monograph 2005; 10: 259-260.
 
18.
Verthelyir D. Sex hormones as immunomodulators in health and disease. International Immunopharmacology 2001; 6: 983-993.
 
19.
Dayan M, Zinger H, Kalush F, et al. The beneficial effects of treatment with tamoxifen and anti-estradiol antibody on experimental systemic lupus erythematosus are associated with cytokine modulations. Immunology 1997; 90: 101-108.
 
20.
Majkowska-Wojciechowska B. Zmiany układu immunologicznego wraz z wiekiem. Żywność dla Zdrowia 2010; 13: 10-13.
 
21.
Huang BL, Chandra S, Shih DQ. Skin manifestations of inflammatory bowel disease. Front Physiol 2012; 3: 1-6.
 
22.
Faulkes RE. Upper limb erythema nodosum: the first presentation of Crohn’s disease. Clin Case Rep 2014; 2: 183-185.
 
23.
Sendur OF. Paraneoplastic rheumatic disorders. Turk J Rheumatol 2012; 27: 18-23.
 
24.
Racanelli V, Prete M, Minoia C, et al. Rheumatic disorders as paraneoplastic syndromes. Autoimmun Rev 2008; 7: 352-358.
 
25.
Simon S, Azevedo SJ, Byrnes JJ. Erythema nodosum heralding recurrent Hodgkin ’s Disease. Cancer 1985; 56: 1470-1472.
 
Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
eISSN:2084-9834
ISSN:0034-6233
Journals System - logo
Scroll to top