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REVIEW PAPER
How compare biologics applied for rheumatic disorders?
Submission date: 2013-09-20
Final revision date: 2014-04-27
Acceptance date: 2014-04-30
Online publication date: 2014-06-04
Publication date: 2014-04-30
Reumatologia 2014;52(2):112-119
KEYWORDS
TOPICS
ABSTRACT
Management of patients with rheumatoid arthritis remains a major clinical problem but introduction of biologics significantly improved therapeutical strategy. Biologics reduce inflammation and its sequelae, including structural joint damage. Single direct comparative trials of biologics are only available, and indirect comparison methods are applied for evaluation of the biologics. Obtained results are not conclusive and are limited by several factors. Metaanalyses and indirect treatment comparison studies of biologic used for management of patients with rheumatoid arthritis are reviewed.
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Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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