Tuftsin-phosphorylcholine treatment of autoimmune diseases – a benefit and a message from helminths?
More details
Hide details
Online publication date: 2017-12-30
Reumatologia 2017;55(6):267–268
Ben-Ami Shor D, Harel M, Eliakim R, Shoenfeld Y. The Hygiene Theory Harnessing Helminths and Their Ova to Treat. Autoimmun Clin Rev Allerg Immunol 2013; 45: 211-216.
Okada H, Kuhn C, Feilet H, Bach JF. The “hygiene hypothesis” for autoimmune and allergic disease an update. Clin Exp Immunol 2010; 160: 1-9.
Elliot DE, Weinstock JV. Helminth-host immunological interactions: prevention and control of immune-mediated diseases. Ann N Y Acad Sci 2012; 1247: 83-96.
Smallwood TB, Giacomin PR, Loukas A, et al. Helminth Immunomodulation in Autoimmune Disease. Front Immunol 2017; 8: 453.
Versini M, Jeandel PY, Bashi T, et al. Unraveling the hygiene hypothesis of helminthes and autoimmunity: origins, pathopshysiology, and clinical applications. BMC Medicine 2015; 13: 81.
Weiser J. Role of Phosphorylcholine in Respiratory Tract Colonization. In: Colonization of Mucosal Surfaces, Nataro J, Cohen P, Mobley H, Weiser J (eds.). ASM Press, Washington 2005; 61-72.
Gao Y, Su Q, Yi Y, et al. Enhanced Mucosal Immune Responses Induced by a Combined Candidate Mucosal Vaccine based on hepatitis A virus and hepatitis E virus Structural Proteins Linked to tuftsin. PLoS One 2015; 10 (4): e0123400.
Ben-Ami Shor D, Bashi T, Lachish J, et al. Phosphorylcholine-tuftsin compound prevents development of Dextran-Sodium- Sulfate induced murine colitis. Implication for the treatment of human inflammatory bowel disease. J Autoimmun 2015; 56: 111-117.
Bashi T, Blank M. Omersel J, et al. Novel Therapeutic Compound Tuftsin-Phosphorylcholine Attenuate Collagen Induced arthritis. Arthritis Rheum 2015; 67 (suppl 10).
Bashi T, Blank M, Ben-Ami Shor D, et al. Successful modulation of murine lupus nephritis with Tuftsin-phosphorylcholine. J Autoimmun 2015; 5: 1-7.
Bashi T, Bizzaro G, Ben-Ami Shor D, et al. The mechanisms behind helminth’s immunomodulation in autoimmunity. Autoimmun Rev 2015; 14: 98-104.
Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.