Digestive tract in patients with systemic sclerosis
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Online publication date: 2006-04-28
Reumatologia 2006;44(2):95-101
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ABSTRACT
Digestive tract is the most common internal organ involved in systemic sclerosis. This process may concern each part of alimentary system, and most frequently consist on motility disturbances or mucosal changes (teleangiectases, protein-losing gastroenteropathy). Their complications are: gastroesophageal reflux, slowdown of oesophago- gastro- intestinal transit, malabsorption syndrome with complicated pathogenesis, and serious hemorrhages. Autoimmunological disorders accompanying scleroderma favor coexistence with celiac disease, Crohn disease and primary biliary cirrhosis. Treatment of symptoms originated from digestive tract in patients with systemic sclerosis include: dietary advices, pharmacotherapy with prokinetics, antibiotics, cholestyramine, and pancreatic enzymes substitution, as well as endoscopic therapy and surgery.
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