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Genetic factors in pathogenesis of rheumatoid arthritis
 
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Online publication date: 2009-08-11
 
 
Reumatologia 2009;47(3):143-150
 
KEYWORDS
ABSTRACT
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder. The course of RA and its prognosis are variable. It may develop and progress slowly or rapidly causing disability and even mortality. The etiology of RA is unknown, but it is thought to have genetic and environmental basis. Familial aggregation of RA allow to suppose, that genetic factors appear to play a major role that can cause disease initiation.
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