EN PL
PRACA PRZEGLĄDOWA
Czynniki genetyczne w patogenezie reumatoidalnego zapalenia stawów
 
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Data publikacji online: 11-08-2009
 
 
Reumatologia 2009;47(3):143-150
 
SŁOWA KLUCZOWE
STRESZCZENIE
Reumatoidalne zapalenie stawów (RZS) jest przewlekłą, układową chorobą autoimmunologiczną. Przebieg choroby jest zróżnicowany, od postaci łagodnych, które są ograniczone do samych stawów, do ciężkich, z występowaniem zmian pozastawowych, co może doprowadzić do inwalidztwa, a nawet śmierci. Nie jest znana etiologia RZS, jednak przypuszcza się, że na występowanie choroby mają wpływ czynniki genetyczne i środowiskowe. Rodzinne występowanie RZS pozwala przypuszczać, że podłoże genetyczne może mieć istotne znaczenie w inicjacji choroby.
 
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