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PRACA PRZEGLĄDOWA
Choroba śródmiąższowa płuc w twardzinie układowej: wyzwania we wczesnej diagnostyce i leczeniu
 
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Data nadesłania: 11-05-2018
 
 
Data ostatniej rewizji: 16-07-2018
 
 
Data akceptacji: 18-07-2018
 
 
Data publikacji online: 31-08-2018
 
 
Data publikacji: 31-08-2018
 
 
Reumatologia 2018;56(4):249-254
 
SŁOWA KLUCZOWE
DZIEDZINY
STRESZCZENIE
Interstitial lung disease (ILD) is a group of lung diseases characterized by thickening of the interstitium surrounding pulmonary alveolar walls. It is related to specific radiographic features in lung imaging and/or the presence of restrictive disorders in pulmonary function tests (PFTs). ILD is one of the leading causes of death in systemic sclerosis patients. Major risk factors of ILD associated with SSc (SSc-ILD) include male sex, diffuse type of cutaneous SSc and presence of anti-Scl-70 antibodies.
SSc-ILD is challenging to diagnose at an early stage as the symptoms are non-specific. The greatest risk of its development is during the 4–5 years after the initial diagnosis of systemic sclerosis. Clinical vigilance at the time, including regular pulmonary function tests and/or high-resolution com-puted tomography (HRCT), is needed. The aim of this paper is to summarize the current knowledge on early diagnostic methods and progression risk factors for SSc-ILD.
 
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