EN PL
REVIEW PAPER
Lesions of alimentary tract in the course of systemic lupus erythematosus
 
More details
Hide details
 
Online publication date: 2013-03-05
 
 
Reumatologia 2013;51(1):36-41
 
KEYWORDS
ABSTRACT
Systemic lupus erythematosus is a chronic autoimmune, inflammatory connective tissue disease in the course of which different organs and systems may be affected. Gastroenterological symptoms are present in 25–40% of patients with active disease. They are usually nonspecific and result from the disease itself or are the side effect of applied therapy. Lesions of the gastrointestinal tract may affect any part of it and may also affect the liver and pancreas. This paper presents the most frequent and the most serious gastrointestinal manifestations in the course of systemic lupus erythematosus including lupus mesenteric vasculitis, protein-losing enteropathy, pneumatosis cystoides intestinalis and lesions of the liver and pancreas.
REFERENCES (43)
1.
Suszek D, Wielosz E, Majdan M. Toczeń rumieniowaty układowy. Lekarz 2008; 12: 43-50. .
 
2.
Majdan M. Toczeń rumieniowaty układowy. Reumatologia 2012; 50: 103-110. .
 
3.
Plomer-Niezgoda E, Maj J, Hryniewicz-Gwóźdź A i wsp. Toczeń trzewny układowy: zasady postępowania. Ocena aktywności choroby. Dermatol Klin 2011; 13: 99-104.
 
4.
Sultan SM, Ioannou Y, Isenberg DA. A review of gastroenterological manifestation of lupus erythematosus. Reumatology 1999, 38: 917-932.
 
5.
Vilardell-Tarre M, Selvo-O’Callaghan A, Ordi-Ros J. Systemic lupus erythematosus In: Digestive involvment in systemic autoimmune disease. Font J, Ramos-Casals M, Rodes J (eds.). Elsevier, Amsterdam 2008; 31-38. .
 
6.
Ziętkiewicz M, Smoleńska Ż, Zdrojewski Z. Zajęcie przewodu po­karmowego w toczniu rumieniowatym układowym – opis przypadku. Ann Acad Med Stetin 2010; 56 Supl. 1: 52-57. .
 
7.
Johnson AE, Cavalcanti FS, Gordon C, et al. Cross-sectional analysis of the differences between patients with systemic lupus erythematosus in England, Brazil and Sweden. Lupus 1994; 3: 501-506.
 
8.
Daruwala C, Mercogliano C, Harder TP. Gastrointestinal manifestations of systemic lupus erythematosus and scleroderma. Clin Med Gastroenterol 2009; 2: 7-12. .
 
9.
Jonsson R, Heyden G, Westberg NG, Nyberg G. Oral mucosal lesions in systemic lupus erythematosus – a clinical, histopathological and immunopathological study. J Reumathol 1984; 11: 38-42.
 
10.
Chua S, Dodd H, Saeed IT, Chakravarty K. Dysphagia in a pa­tient with lupus and review of the literature. J Rheumatol 2002; 11: 322-324.
 
11.
Saab S, Corr MP, Weisman MH. Corticosteroids and systemic lupus erythematosus pancreatitis: a case series. J Rheumatol Aprol 1998; 25: 801-806.
 
12.
Ginzler EM, Aranow C. Prevention and treatment of adverse effects of corticosteroids in systemic lupus erythematosus. Baillieres Clin Rheumatol 1998; 12: 495-510.
 
13.
Drenkard C, Villa AR, Reyes E, Abello M, Alarcón-Segovia D. Vasculitis in systemic lupus erythematosus. Lupus 1997; 6: 235-242. .
 
14.
Tian XP, Zhang X. Gastrointestinal involvement in systemic lupus erythematosus: insight into pathogenesis, diagnosis and treatment. World J Gastroenterol 2010; 16: 2971-2977.
 
15.
Lee CK, Ahn MS, Lee EY, et al. Acute abdominal pain in systemic lupus erythematosus: focus on lupus enteritis (gastrointestinal vasculitis). Ann Rheum Dis 2002; 61: 547-550.
 
16.
Kwok SK, Seo SH, Ju JH, et al. Lupus enteritis: clinical characteristics, risk factor for relapse and association with anti-endothelial cell antibody. Lupus 2007; 16: 803-809.
 
17.
Buck AC, Serebro LH, Quinet RJ. Subacute abdominal pain requiring hospitalization in a systemic lupus erythematosus patient: a retrospective analysis and review of the literature. Lupus 2001; 10: 491-495.
 
18.
Ju JH, Min JK, Jung CK, et al. Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE. Nat Rev Rheumatol 2009; 5: 273-281.
 
19.
Endo H, Kondo Y, Kawagoe K, et al. Lupus enteritis detected by capsule endoscopy. Intern Med 2007; 46: 1621-1622.
 
20.
Prouse PJ, Thompson EM, Gumpel JM. Systemic lupus erythematosus and abdominal pain. Br J Rheumatol 1983; 22: 172-175.
 
21.
Mok CC, Ying KY, Mak A, To CH, Szeto ML. Outcome of protein-losing gastroenteropathy in systemic lupus erythematosus treated with prednisolone and azathioprine. Rheumatology (Oxford) 2006; 45: 425-429.
 
22.
Zheng WJ, Tian XP, Li L, Jing HL, et al. Protein-losing enteropathy in systemic lupus erythematosus: analysis of the clinical features of fifteen patients. J Clin Rheumatol 2007; 13: 313-316.
 
23.
Gornisiewicz M, Rodriguez M, Smith JK, et al. Protein-losing enteropathy in a young African-American woman with abdominal pain, diarrhea and hydronephrosis. Lupus 2001; 10: 835-840. .
 
24.
Kim YG, Lee CK, Byeon JS, et al. Serum cholesterol in idiopathic and lupus-related protein-losing enteropathy. Lupus 2008; 17: 575-579.
 
25.
Yazici Y, Erkan D, Levine DM, et al. Protein-losing enteropathy in systemic lupus erythematosus: report of a severe, persistent case and review of pathophysiology. Lupus 2002; 11:119-123.
 
26.
Oh DC, Ng TM, Ho J, Leong KP. Systemic lupus erythematosus with concurrent protein-losing enteropathy and primary sclerosing cholangitis: a unique association. Lupus 2006; 15: 102-104. .
 
27.
Mizoguchi F, Nanki T, Miyasaka N. Pneumatosis cystoides intestinalis following lupus enteritis and peritonitis. Intern Med 2008; 47: 1267-1271.
 
28.
Jaimes-Hernandez J, Aranda-Peirera P, Melendez-Mercado CI. Eosinophilic enteritis in association with systemic lupus erythematosus. Lupus 2009; 18: 452-456.
 
29.
Medeiros DA, Isenberg DA. Systemic lupus erythematosus and ulcerative colitis. Lupus 2009; 18: 762-763.
 
30.
Su KY, Tsai ST, Tsay SH, et al. A patient with systemic lupus erythematosus and Crohn's disease complicated with massive lower gastrointestinal bleeding, mimicking intestinal vasculitis. Lupus 2008; 17: 1049-1050. .
 
31.
Van Hoek B. The spectrum of liver disease in systemic lupus erythematosus. Neth J Med 1996; 48: 244-253.
 
32.
Daniluk J, Wolak A, Łozowski CT, et al. Systemic lupus erythematosus and hepatic diseases. Exp Clin Hepatology 2008; 4: 41-47.
 
33.
Łozowski CT, Daniluk J. Zmiany w wątrobie w przebiegu chorób układowych. Terapia 2001; 9: 19-23. .
 
34.
Matsumoto T, Kobayashi S, Shimizu H, et al. The liver in collagen diseases: pathologic study of 160 cases with particular reference to hepatic arteritis, primary biliary cirrhosis, autoimmune hepatitis and nodular regenerative hyperplasia of the liver. Liver 2000; 20: 366-375.
 
35.
Tojo J, Ohira H, Abe K, et al. Autoimmune hepatitis accompanied by systemic lupus erythematosus. Intern Med 2004; 43: 258-262.
 
36.
Hanson J, Bossingham D. Lupus-like syndrome associated with simvastatin. Lancet 1998, 352: 1070.
 
37.
Breuer GS, Baer A, Dahan D, Nesher G. Lupus-associated pancreatitis. Autoimmun Rev 2006; 5: 314-318.
 
38.
Nesher G, Breuer GS, Temprano K, et al. Lupus-associated pancreatitis. Semin Arthritis Rheum 2006; 35: 260-267.
 
39.
Larin~o Noia J, Macias Garcia F, Seijo Rios S, et al. Pancreatitis and systemic lupus erythematosus. Rev Esp Enferm Dig 2009; 101: 571-579. .
 
40.
Makol A, Petri M. Pancreatitis in systemic lupus erythematosus: frequency and associated factors – a review of the Hopkins Lupus Cohort. J Rheumatol 2010; 37: 341-345.
 
41.
Wang F, Wang NS, Zhao BH, Tang LQ. Acute pancreatitis as an initial symptom of systemic lupus erythematosus: a case report and review of the literature. World J Gastroenterol 2005; 11: 4766-4768.
 
42.
Pascual-Ramos V, Duarte-Rojo A, Villa AR, et al. Systemic lupus erythematosus as a cause and prognostic factor of acute pancreatitis. J Rheumatol 2004; 31: 707-712.
 
43.
Takeno M, Ishigatsubo Y. Intestinal manifestations in systemic lupus erythematosus. Intern Med 2006; 45: 41-42.
 
Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
eISSN:2084-9834
ISSN:0034-6233
Journals System - logo
Scroll to top