Degenerative lesions in intervertebral discs rank among the most common causes of spinal pain syndromes. Conservative treatment, pharmacotherapy and rehabilitation focus on the elimination of pain symptoms without addressing the underlying cause of the pain. Surgical techniques applied to date have, in turn, eliminated the cause of the pain while failing to halt the degeneration process affecting the discs. The future of the treatment of degenerative disc lesions lies in methods affecting the nutrition, improving the hydration and stimulating the regeneration of intervertebral discs, as outlined in the present study.