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CASE REPORT
The variety of clinical symptoms as a cause of difficulty in correct diagnosis of granulomatosis with polyangiitis
Submission date: 2013-08-14
Final revision date: 2014-01-19
Acceptance date: 2014-02-05
Online publication date: 2014-03-23
Publication date: 2014-02-28
Reumatologia 2014;52(1):77-81
KEYWORDS
TOPICS
Vasculitis - aetiology, pathogenesis, clinical features and treatmentDiagnostics and imaging in rheumatic diseases
ABSTRACT
The essence of granulomatosis with polyangiitis (GPA) is the occurrence of necrotizing granulomatous vasculitis of medium and small vessels. Particularly, the respiratory tract and the kidneys are predisposed to this disease.
We present the case of a 65-year-old woman in whom GPA was diagnosed. The occurrence of non-specific clinical signs contributed to the fact that the disease remains undiagnosed for a long time. The predominant symptom was treatment-resistant, long-term skin ulceration in the right leg.
No therapeutic effect of long-term treatment of ulcers should lead to further evaluation and a search for other causes of symptoms. Implementation of effective treatment prevents complications in GPA, which is possible by establishing a rapid diagnosis.
We present the case of a 65-year-old woman in whom GPA was diagnosed. The occurrence of non-specific clinical signs contributed to the fact that the disease remains undiagnosed for a long time. The predominant symptom was treatment-resistant, long-term skin ulceration in the right leg.
No therapeutic effect of long-term treatment of ulcers should lead to further evaluation and a search for other causes of symptoms. Implementation of effective treatment prevents complications in GPA, which is possible by establishing a rapid diagnosis.
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Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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