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Matrix risk models for the prediction of rapid radiographic progression in patients with rheumatoid arthritis
 
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Online publication date: 2012-12-21
 
 
Reumatologia 2012;50(6):512-514
 
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ABSTRACT
Rapid radiographic progression (RRP) in rheumatoid arthritis (RA) occurs in a small percentage of patients. The use of effective therapy can slow radiographic progression in these patients. Rapid identification of risk factors for RRP is therefore important for patients with RA. Using a single variable affecting RRP may be of limited importance. Much more effective is a combination of many variables affecting RRP. For this purpose, matrix models for predicting RRP in patients with RA were prepared. Data from patients from the clinical trials ASPIRE, ATTRACT and BEST were used.
The designed matrix risk models for the prediction of RRP could help rheumatologists in their daily practice in making decisions about the use of treatment strategies in patients with RA. They allow one to assess the risk of RRP in each patient taking into account the combination of specific risk factors. They require the use of several variables that are easy to evaluate, take into account the different treatment options and are easy to use.
 
REFERENCES (13)
1.
Smolen JS, Landewé R, Breedveld FC, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 2010; 69: 964-975.
 
2.
Wiland P. Czynniki prognostyczne progresji radiologicznej w reumatoidalnym zapaleniu stawów. Reumatologia 2010; 48: 213-214.
 
3.
Vastesaeger N, Xu S, Aletaha D, et al. A pilot risk model for the prediction of rapid radiographic progression in rheumatoid arthritis. Rheumatology (Oxford) 2009; 48: 1114-1121.
 
4.
Visser K, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, et al. A matrix risk model for the prediction of rapid radiographic progression in patients with rheumatoid arthritis receiving different dynamic treatment strategies: post hoc analyses from the BeSt study. Ann Rheum Dis 2010; 69: 1333-1337.
 
5.
Smolen JS, Aletaha D. Monitoring rheumatoid arthritis. Curr Opin Rheumatol 2011; 23: 252-258.
 
6.
Conroy RM, Pyörälä K, Fitzgerald AP, et al. SCORE project group Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003; 24: 987-1003.
 
7.
St Clair EW, van der Heijde DM, Smolen JS, et al. Active-Controlled Study of Patients Receiving Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset Study Group. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. Arthritis Rheum 2004; 50: 3432-3443.
 
8.
Lipsky PE, van der Heijde DM, St Clair EW, et al. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheu­matoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 2000; 343: 1594-1602.
 
9.
Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial. Arthritis Rheum 2005; 52: 3381-3390.
 
10.
Bruynesteyn K, Boers M, Kostense P, et al. Deciding on progression of joint damage in paired films of individual patients: smallest detectable difference or change. Ann Rheum Dis 2005; 64: 179-182. .
 
11.
Bruynesteyn K, van der Heijde D, Boers M, et al. Determination of the minimal clinically important difference in rheumatoid arthritis joint damage of the Sharp/van der Heijde and Larsen/Scott scoring methods by clinical experts and comparison with the smallest detectable difference. Arthritis Rheum 2002; 46: 913-920.
 
12.
Sharp JT, Bluhm GB, Brook A, et al. Reproducibility of multiple-observer scoring of radiologic abnormalities in the hands and wrists of patients with rheumatoid arthritis. Arthritis Rheum 1985; 28: 16-24.
 
13.
Prevoo ML, van't Hof MA, Kuper HH, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-48.
 
Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
eISSN:2084-9834
ISSN:0034-6233
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