REVIEW PAPER
Treatment of systemic lupus erythematosus. Part II. The role of biologic agents
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Online publication date: 2012-12-21
Reumatologia 2012;50(6):515-521
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ABSTRACT
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology, characterized by multi-organ involvement, flares and complete or partial remission periods, resulted in increased morbidity and mortality. Symptomatic drugs, corticosteroids, antimalarial and immunosuppressive agents are effective in most of SLE patients. In patients with SLE resistant to conventional treatment new therapies must be considered. We present the role of biologic agents in the treatment of SLE, include currently used (belimumab and rituximab) and tested in clinical trials.
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