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O czasopiśmie
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Książki i Konferencje
4/2016 vol. 54
Pobierz cytowanie
PRACA PRZEGLĄDOWA
Medycyna personalizowana w reumatologii
Anna Kłak
,
 
Agnieszka Paradowska-Gorycka
,
 
Brygida Kwiatkowska
,
 
Filip Raciborski
 
 
 
Więcej
Ukryj
 
Data nadesłania: 22-07-2016
 
 
Data ostatniej rewizji: 10-08-2016
 
 
Data akceptacji: 12-08-2016
 
 
Data publikacji online: 05-10-2016
 
 
Data publikacji: 31-08-2016
 
 
Reumatologia 2016;54(4):177-186
DOI: https://doi.org/10.5114/reum.2016.62472
 
 
Artykuł (PDF)
Referencje (44)
 
SŁOWA KLUCZOWE
personalized medicine
rheumatoid arthritis
biomarkers
genetic test
 
DZIEDZINY
Nowe terapie w chorobach reumatycznych
 
STRESZCZENIE
In the era of the 21st century, rheumatoid arthritis (RA) is still poorly characterized. Rheumatoid
arthritis is a common but heterogeneous disease, not only in the course and clinical symptoms, but also in the clinical response to treatment. Now it is known that early, correct diagnosis and starting treatment with disease-modifying drugs (DMARDs), of which methotrexate (MTX) remains the gold standard in the treatment of RA, is crucial in order to prevent joint destruction, functional disability and an unfavourable disease outcome. Early diagnosis of rheumatoid arthritis is significant in so much as the primary treatment can be started better. Pharmacogenetic and pharmacogenomic studies, which help determine the genetic profile of individual patients, may bring us closer to personalized medicine. Further studies on RA should allow for the identification of disease-specific genes at the stage when their tolerance by the organism is still preserved (before auto-aggression develops).
 
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Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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