Bieżący numer
Archiwum
Online first
O czasopiśmie
Redakcja
Rada Naukowa
Wydawca
Standardy etyczne i procedury
Bazy indeksacyjne
Recenzenci
Recenzenci Honorowi
Prenumerata
Kontakt
Najczęściej czytane artykuły
Dla autorów
Opłata za przetwarzanie artykułu (APC)
Książki i Konferencje
Książki
Konferencje
SARS CoV-2/COVID-19
KRÓTKIE DONIESIENIE
Polymyalgia rheumatica with normal inflammatory indices at the time of diagnosis: can we just move a step forward?
1
Internal and Geriatric Medicine Department, Rheumatologic Outpatient Clinic Hospital “Mariano Lauro”, Sant’Angello, Italy
2
Department of Rheumatology, Internal Medicine, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Poland
Data nadesłania: 08-04-2020
Data akceptacji: 04-05-2020
Data publikacji online: 29-06-2020
Data publikacji: 29-06-2020
Reumatologia 2020;58(3):184-186
SŁOWA KLUCZOWE
DZIEDZINY
Cytokiny, mediatory zapalenia i odporność w chorobach reumatycznychZapalenia naczyń - etiologia, patogeneza, obraz kliniczny i leczenie
STRESZCZENIE
The existence of polymyalgia rheumatica (PMR) with normal inflammatory indices at the time of diagnosis still represents a diagnostic conundrum. According to the literature, some patients with PMR following immune checkpoint inhibitory therapy had normal values of both erythrocyte sedimentation rate and C-reactive protein concentrations at the time of diagnosis. In this short communication we investigated the possibility that in some patients with PMR the main pathogenic mechanism is constituted by inhibition of some checkpoints, such as programmed death receptor-1, programmed death ligand 1, and “cytotoxic” lymphocyte antigen 4. In these patients, the pathogenetic mechanisms underlying PMR can act much more upstream than commonly suggested. Also, we addressed the question of whether these patients should be considered as affected by PMR-like syndromes or by PMR subset.
REFERENCJE (26)
1.
Bird HA, Leeb BF, Montecucco CM, et al. A comparison of the sensitivity of diagnostic criteria for polymyalgia rheumatica. Ann Rheum Dis 2005; 64: 626-629, DOI: 10.1136/ard.2004.025296.
2.
Dasgupta B, Cimmino MA, Kremers HM, et al. 2012 Provisional Classification Criteria for Polymyalgia Rheumatica: A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative. Ann Rheum Dis 2012; 71: 484-492, DOI: 10.1136/annrheumdis-2011-200329.
3.
Manzo C, Milchert M. Polymyalgia rheumatica with normal values of both erythrocyte sedimentation rate and C-reactive protein concentration at the time of diagnosis: a four-point guidance. Reumatologia 2018; 56: 1-2, DOI: 10.5114/reum.2018.74740.
4.
Manzo C, Milchert M, Natale M, Brzosko M. Polymyalgia Rheumatica With Normal Values of Both Erythrocyte Sedimentation Rate and C-reactive Protein Concentration at the Time of Diagnosis. Rheumatology (Oxford) 2019; 5: 921-923, DOI: 10.1093/rheumatology/key431.
5.
Topalian SL, Drake CG, Pardoll DM. Immune Checkpoint Blockade: A Common Denominator Approach in Cancer Therapy. Cancer Cell 2015; 27: 450-461, DOI: 10.1016/j.ccell.2015.03.001.
6.
Hargadon KM, Johnson CE, Williams CJ. Immune Checkpoint Blockade Therapy for Cancer: An Overview of FDA approved Immune Checkpoint Inhibitors. Int Immunopharmacol 2018; 62: 29-39, DOI: 10.1016/j.intimp.2018.06.001.
7.
Wolchok JD, Neyns B, Linette G, et al. Ipilimumab Monotheraphy in Patients With Pretreated Advanced Melanoma: A Randomized, Double-Bind, Multicentre, Phase 2, Dose-Ranging Study. Lancet Oncol 2010; 1: 155-164, DOI: 10.1016/S1470-2045(09)70334-1.
8.
He XS, Gershwin ME, Ansari AA. Checkpoint-based Immunotherapy for Autoimmune Diseases – Opportunities and Challenges. J Autoimmun 2017; 79: 1-3, DOI: 10.1016/j.jaut.2017.02.004.
9.
Calabrese LH, Calabrese C, Cappelli LC. Rheumatic Immune-Related Adverse Events From Cancer Immunotherapy. Nat Rev Rheumatol 2018; 14: 569-579, DOI: 10.1038/s41584-018-0074-9.
10.
Richter MD, Crowson C, Kottschade LA, et al. Rheumatic Syndromes Associated With Immune Checkpoint Inhibitors: A Single-Center Cohort of Sisty-One Patients. Arthritis Rheumatol 2019; 71: 468-475, DOI: 10.1002/art.40745.
11.
Shahin J, Hudson M, Fifi-Mah A, Ye C. Immune-related Adverse Events Associated With Cancer Immunotherapy: A Review for the Practicing Rheumatologist. J Rheumatol 2020; 47: 156-175, DOI: 10.3899/jrheum.190084.
12.
Chan KK, Bass AR. Checkpoint Inhibitor-Induced Polymyalgia Rheumatica Controlled by Cobimetinib, a MEK ½ Inhibitor. Ann Rheum Dis 2019; 78: e70, DOI: 10.1136/annrheumdis-2018-213672.
13.
Garel B, Krankimel N, Trouvin AP, et al. Pembrolizumab-induced Polymyalgia Rheumatica in Two Patients With Metastatic Melanoma. Joint Bone Spine 2017; 84: 233-234, DOI: 10.1016/j.jbspin.2016.01.007.
14.
Kuswanto WF, MacFarlane LA, Gedmintas L, et al. Rheumatologic Symptoms in Oncologic Patients on PD-1 Inhibitors. Semin Arthritis Rheum 2018; 47: 907-910, DOI: 10.1016/j.semarthrit.2017.10.018.
15.
Salem JE, Manouchehri A, Moey M, et al. Cardiovscular Toxicities Associated With Immune Checkpoint Inhibitors: An Observational, Retrospective, Pharmacovigilance Study. Lancet Oncol 2018; 19: 1579-1589, DOI: 10.1016/S1470-2045(18)30608-9.
16.
Calabrese C, Cappelli LC, Kostine M, et al. Polymyalgia rheumatica-like syndrome from chreckpoint inhibitor therapy: case series and systematic review of the literature. RMD Open 2019; 5: e000906, DOI: 10.1136/rmdopen-2019-000906.
17.
Guggino G, Ferrante A, Macaluso F, et al. Pathogenesis of Polymyalgia Rheumatica. Reumatismo 2018; 70: 10-17, DOI: 10.4081/reumatismo.2018.1048.
18.
Boiardi L, Casali B, Farnetti E, et al. Relationship Between Interleukin 6 Promoter Polymorphism at Position -174, IL-6 Serum Levels, and the Risk of Relapse/Recurrence in Polymyalgia Rheumatica. J Rheumatol 2006; 33: 703-708.
19.
Doria A, Zen M, Bettio S, et al. Autoinflammation and Autoimmunity: Brindging the Divide. Autoimmun Rev 2012; 12: 22-30, DOI: 10.1016/j.autrev.2012.07.018.
20.
Bonafè M, Olivieri F, Cavallone L, et al. A Gender-Dependent Genetic Predisposition to Produce High Levels of IL-6 is Detrimental for Longevity. Eur J Immunol 2001; 31: 2357-2361, DOI: 10.1002/1521-4141(200108)31:8<.
21.
Zhang H, Watanabe R, Berry GJ, et al. Immunoinhibitory Checkpoint Deficiency in Medium and Large Vessel Vasculitis. Proc Natl Acad Sci USA 2017; 114: E970-E979, DOI: 10.1073/pnas.1616848114.
22.
Weyand CM, Berry GJ, Goronzy JJ. The Immunoinhibitory PD-1/PD-L1 Pathway in Inflammatory Blood Vessel Disease. J Leukoc Biol 2018; 103: 565-575, DOI: 10.1189/jlb.3MA0717-283.
23.
Gonzalez-Gay MA. Giant Cell Arteritis and Polymyalgia Rheumatica: Two Different but Often Overlapping Conditions. Semin Arthritis Rheum 2004; 33: 289-293, DOI: 10.1016/j.semarthrit.2003.09.007.
24.
Buttgereit F, Dejaco C, Matteson EL, Dasgupta B. Polymyalgia Rheumatica and Giant Cell Arteritis: Systematic Review. JAMA 2016; 315: 2442-2458, DOI: 10.1001/jama.2016.5444.
25.
Milchert M, Brzosko M. Diagnosis of Polymyalgia Rheumatica Usually Means a Favourable Outcome for Your Patient. Indian J Med Res 2017; 145: 593-600, DOI: 10.4103/ijmr.IJMR_298_17.
26.
Owen CE, Liew DFL, Buchanan RRC. Musculotendinous Inflammation: The Defining Pathology of Polymyalgia Rheumatica? J Rheumatol 2019; 46: 1552-1555, DOI: 10.3899/jrheum.190367.
Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Udostępnij
ARTYKUŁ POWIĄZANY
| eISSN: | 2084-9834 |
| ISSN: | 0034-6233 |
Przetwarzamy dane osobowe zbierane podczas odwiedzania serwisu. Realizacja funkcji pozyskiwania informacji o użytkownikach i ich zachowaniu odbywa się poprzez dobrowolnie wprowadzone w formularzach informacje oraz zapisywanie w urządzeniach końcowych plików cookies (tzw. ciasteczka). Dane, w tym pliki cookies, wykorzystywane są w celu realizacji usług, zapewnienia wygodnego korzystania ze strony oraz w celu monitorowania ruchu zgodnie z Polityką prywatności. Dane są także zbierane i przetwarzane przez narzędzie Google Analytics (więcej).
Możesz zmienić ustawienia cookies w swojej przeglądarce. Ograniczenie stosowania plików cookies w konfiguracji przeglądarki może wpłynąć na niektóre funkcjonalności dostępne na stronie.
Możesz zmienić ustawienia cookies w swojej przeglądarce. Ograniczenie stosowania plików cookies w konfiguracji przeglądarki może wpłynąć na niektóre funkcjonalności dostępne na stronie.
