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Selected problems of biologic therapy in rheumatoid arthritis patients – pregnancy during therapy. Case reports
 
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Online publication date: 2013-03-05
 
 
Reumatologia 2013;51(1):93-95
 
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ABSTRACT
Preparation for being pregnant and pregnancy management in rheumatoid arthritis (RA) constitute an important clinical problem. An unfavorable influence on pregnancy may be caused by inflammation per se and organ involvement during RA, but also by applied therapy. Few observations exist concerning the course of pregnancy in RA patients treated with biologics. In this study we present two cases of RA patients, who became pregnant during biologic therapy.
 
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Hazes JM, Coulie PG, Geenen V, et al. Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use. Rheumatology (Oxford) 2011; 50: 1955-1968.
 
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Verstappen SM, King Y, Watson KD, et al. Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register. Ann Rheum Dis 2011; 70: 823-826.
 
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Andreoli L, Bazzani C, Taraborelli M, et al. Pregnancy in autoimmune rheumatic diseases: the importance of counselling for old and new challenges. Autoimmun Rev 2010; 10: 51-54.
 
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eISSN:2084-9834
ISSN:0034-6233
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