ORIGINAL PAPER
Clinical follow-up studies of a family with an aggregation of arthritis and extra-articular symptoms
Online publication date: 2009-12-29
Reumatologia 2009;47(5):258-267
KEYWORDS
ABSTRACT
Acute, recurrent, seronegative oligoarthritis starting in childhood is observed in two consecutive generations of the same family (in 12 cases). Extra-articular symptoms are also observed: hepato-and/or splenomegaly, myocarditis, frequent infections as well as high values of ESR and CRP and decreased haemoglobin level. In some patients there occurred leucopenia, hypergam-maglobulinaemia and haematuria. HLA-B27 was negative in all members of the family. Histological examination of synovium, performed in 3 cases after synovectomy, yielded an atypical picture. The described syndrome does not correspond to the criteria of any definite rheumatic disease.
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Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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