Remission in lupus nephritis – report of three cases

In this paper we present the course of lupus nephritis (LN) of three patients who were treated aggressively from the onset of the disease with glucocorticoid (GC), cyclophosphamide (CYC) and then mycophenolate mofetil (MMF). In two patients class IV of LN was confirmed in the renal biopsy and secondary antiphospholipid syndrome (APS) was diagnosed. Applying the treatment regimen based on CYC in the induction of remission and then MMF as the maintenance therapy led to the remission of kidney symptoms, but both stages of treatment were correlated with infectious complications.
Applying aggressive treatment from the onset of the disease while considering simultaneously the risk of possible complications gives the chance to achieve complete remission of LN.

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