ORIGINAL PAPER
Long-term follow-up of Slovakian patients with chondrocalcinosis: implications for disease patterns
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Online publication date: 2012-06-27
Reumatologia 2012;50(3):195-201
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ABSTRACT
Objective: This paper reports the long-term follow-up of Slovakian patients with chondrocalcinosis and significant hand involvement to evaluate how these patients will be defined by criteria proposed to classify calcium pyrophosphate disorder patients.
Material and methods: Patients with chondrocalcinosis in the village of Velka Maca were examined and seven with prominent hand findings were identified. X-rays, laboratory tests and physical findings were reviewed.
Results: These patients with prominent metacarpal phalangeal and proximal inter-phalangeal involvement had occasional swan neck deformities but only firm thickening of the joints. X-rays showed chondrocalcinosis and osteoarthritis-like changes (Table I). These patients fit the classification of polyarticular non-inflammatory disease without acute flares (Fig. 1, 2).
Conclusions: In this population in which chondrocalcinosis had been first reported, patients with hand involvement did not show any examples of “pseudo rheumatoid arthritis” (polyarticular inflammatory arthritis) but rather non-inflammatory involvement.
REFERENCES (15)
1.
Zitnan D, Sitaj S. Chondrocalcinosis articularis. Section 1 clinical and radiological studies. Ann Rheum Dis 1963; 22: 142-152.
2.
Zitnan D, Sitaj S. Natural course of articular chondrocalcinosis. Arthitis Rheum 1976; 19: 363-390.
3.
Reginato AJ. Articular chondrocalcinosis in the Chiloe islanders. Arthritis Rheum 1976; 19: 395-404.
4.
McCarty DJ, Kohn NN, Faires JS. The significance of calcium phosphate crystals in the synovial fluid of arthritic patients: the “pseudogout syndrome”: I. Clinical aspects. Ann Intern Med 1962; 56: 711-737.
5.
McCarty DJ. Calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 1976; 19 (Suppl): 275-286.
6.
Zhang W, Doherty M, Bardin T, et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 2011; 70: 563-570.
7.
Schlesinger N, Hassett AL, Neustadter L, Schumacher HR Jr. Does acute synovitis (pseudogout) occur in patients with chronic pyrophosphate arthropathy (pseudo-osteoarthritis)? Clin Exp Rheumatol 2009; 27: 940-944.
8.
Žitňan D, Rovenský J. Crystal induced arthropathies. Acta Rheumatologica et Balneologica Pistiniana 1993; 11: 1-64.
9.
Panush RS, Carias K, Kraver N, Rosenstein ED. Acute arthritis in the hospital: comparison of rheumatologic with nonrheumatologic care. J Clin Rheumatol 1995; 1: 74-80.
10.
Nalbant S, Martinez JA, Kitumnuaypong T, et al. Synovial fluid features and their relations to osteoarthritis severity: new findings from sequential studies. Osteoarthritis Cartilage 2003; 11: 50-54.
11.
Utsinger PD, Resnick D, Zvaifler NJ. Wrist arthropathy in calcium pyrophosphate dihydrate deposition disease. Arthritis Rheum 1975; 18: 485-491.
12.
Doherty M, Watt I, Dieppe PA. Localised chondrocalcinosis in post-meniscectomy knees. Lancet 1982; 1: 1207-1210.
13.
Wilkins E, Dieppe P, Maddison P, Evison G. Osteoarthritis and articular chondrocalcinosis in the elderly. Ann Rheum Dis 1983; 42: 280-284.
14.
Rothschild B, Yakubov LE. Prospective 6-month, double-blind trial of hydroxychloroquine treatment of CPPD. Compr Ther 1997; 23: 327-331.
15.
Doherty M, Dieppe PA. Double blind, placebo controlled trial of magnesium carbonate in chronic pyrophosphate arthropathy. Ann Rheum Dis 1983; 42: 106-107.
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