Sjögren’s syndrome: current view on classification criteria and disease activity indexes
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Online publication date: 2010-12-20
Reumatologia 2010;48(6):436-441
Sjögren’s syndrome (SS) is a chronic autoimmune disease that mainly affects the exocrine glands and leads to the sicca complex. There is often a systemic involvement (extraglandular manifestations) and increased occurrence of B cell lymphoma. The pathogenesis of the disease still remains unknown. The current diagnostic/classification criteria for SS are controversial and not universally accepted. The absence of established classification criteria for SS contributes to delays in the diagnosis. In 2003, the Sjögren’s International Collaborative Clinical Alliance (SICCA) was founded to develop standardized classification/diagnostic criteria for SS. To assess the effectiveness of new therapies, in 2007 and 2009, three disease activity indexes were developed: SSDAI (Sjögren’s Syndrome Disease Activity Index), SCAI (Sjögren’s Systemic Clinical Activity Index) and ESSDAI (EULAR Sjögren’s Syndrome Disease Activity Index). The purpose of this review is to summarize current classification criteria and disease activity indexes for SS.
Nikolov NP, Illei GG. Pathogenesis of Sjögren's syndrome. Curr Opin Rheumatol 2009; 21: 465-470.  .
Bloch KJ, Buchanan WW, Wohl MJ, et al. Sjögren’s syndrome: a clinical, pathological, and serological study of sixty-two cases. Medicine (Baltimore) 1965; 44: 187-231.  .
Manthorpe R, Oxholm P, Prause JU, et al. The Copenhagen criteria for Sjögren's syndrome. Scand J Rheumatol Suppl 1986; 61: 19-21.  .
Homma M, Tojo T, Akizuki M, et al. Criteria for Sjögren’s syndrome in Japan. Scand J Rheumatol Suppl 1986; 61: 26-27.  .
Skopouli FN, Drosos AA, Papaioannou T, et al. Preliminary diagnostic criteria for Sjögren’s syndrome. Scand J Rheumatol Suppl 1986; 61: 22-25.  .
Fox RI, Robinson CA, Curd JG, et al. Sjögren’s syndrome: proposed criteria for classification. Arthritis Rheum 1986; 29: 577-585.  .
Daniels TE, Talal N. Diagnosis and differential diagnosis of Sjögren’s syndrome. In: Sjögren’s syndrome: clinical and immunological aspects, Talal N, Moutsopoulos HM, Kassan SS (eds). Springer, Berlin 1987; 193-199.  .
Vitali C, Bombardieri S, Moutsopoulos HM, et al. Preliminary criteria for the classification of Sjögren’s syndrome: results of a prospective concerted action supported by the European Community. Arthritis Rheum 1993; 36: 340-347.  .
Fujibayashi T. Revised diagnostic criteria for Sjögren’s syndrome. Rheumatology 2000; 24: 421-428. .
Vitali C, Bombardieri S, Jonsson R, et al. Classification criteria for Sjögren’s syndrome: a revised version of the European criteria proposed by the American–European Consensus Group. Ann Rheum Dis 2002; 61: 554-558. .
Galvez J, Saiz E, Lopez P, et al. Diagnostic evaluation and classification criteria in Sjögren's syndrome. Joint Bone Spine 2009; 76: 44-49. .
Daniels TE, Criswell LA, Shiboski C, et al. An early view of the international Sjögren's syndrome registry. Arthritis Rheum 2009; 61: 711-714. .
Vitali C, Palombi G, Baldini C, et al. Sjögren’s Syndrome Disease Damage Index and Disease Activity Index: scoring systems for the assessment of disease damage and disease activity in Sjögren’s syndrome, derived from an analysis of a cohort of Italian patients. Arthritis Rheum 2007; 56: 2223-2231. .
Bowman SJ, Sutcliffe N, Isenberg DA, et al. Sjögren’s Syndrome Clinical Activity Index (SCAI): a systemic disease activity measure for use in clinical trials in primary Sjögren’s syndrome. Rheumatology (Oxford) 2007; 46: 1845-1851. .
Seror R, Ravaud P, Bowman SJ, et al. EULAR Sjogren's syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogren's syndrome. Ann Rheum Dis 2010; 69: 1103-1109. .
Seror R, Mariette X, Bowman S, et al Accurate detection of changes in disease activity in primary Sjögren's syndrome by the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index. Arthritis Care Res (Hoboken) 2010; 62: 551-558. .
Camper A, Isenberg D. Primary Sjögren's syndrome activity and damage indices comparison. Eur J Clin Invest 2010; 40: 636-644.
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