EN PL
 
EN PL
Bieżący numer
Archiwum
Online first
O czasopiśmie
Dla autorów
Książki i Konferencje
6/2009 vol. 47
Pobierz cytowanie
PRACA PRZEGLĄDOWA
Znaczenie infekcji w chorobach autoimmunologicznych
Elżbieta Smolewska
 
 
 
Więcej
Ukryj
 
Data publikacji online: 08-04-2010
 
 
Reumatologia 2009;47(6):332-338
 
Artykuł (PDF)
Referencje (61)
 
SŁOWA KLUCZOWE
infekcja
środowisko
choroby autoimmunologiczne
 
STRESZCZENIE
Do rozwoju chorób autoimmunologicznych, w których dochodzi do przełamania przez układ immunologiczny tolerancji własnych antygenów w rezultacie zadziałania szkodliwych czynników na różne tkanki i narządy, prowadzi prawdopodobnie kompleks czynników endogennych (w tym genetycznych, immunologicznych lub hormonalnych) oraz środowiskowych. Spośród tych ostatnich najważniejszym elementem wydają się różnego typu infekcje, zarówno wirusowe, bakteryjne, jak i pasożytnicze. Wiele obserwacji wskazuje jednak na fakt, że niektóre zakażenia mogą wywierać działanie ochronne przed chorobami z autoagresji. Potencjalnie patogenna lub protekcyjna rola infekcji w rozwoju chorób autoimmunologicznych i prawdopodobne mechanizmy tych zjawisk stanowią przedmiot niniejszej pracy.
 
REFERENCJE (61)
1.
Shoenfeld Y, Zandmann-Goddard G, Stojanovich L, et al. The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases. IMAJ 2008; 10: 8-12. .
Google Scholar
 
 
2.
Kivity S, Agmon-Levin N, Blank M, et al. Infections and autoimmunity – friends or foes? Trends Immunol 2009; 30: 409-414. .
Google Scholar
 
 
3.
Doria A. Infections, rheumatism and autoimmunity: The conflicting relationship between humans and their environment. Autoimmun Rev 2008; 8: 1-4. .
Google Scholar
 
 
4.
Ercolini AM, Miller SD. The role of infections in autoimmune diseases. Clin Exp Immunol 2008; 155: 1-15. .
Google Scholar
 
 
5.
Bach JF. Infections and autoimmune diseases. J Autoimmun 2005; 25: 74-80. .
Google Scholar
 
 
6.
Mackay IR, Leskovek NV, Rose NR. Cell damage and autoimmunity; a critical appraisal. J Autoimmun 2008; 30: 5-11. .
Google Scholar
 
 
7.
Fujinami RS, Oldstone MB. Molecular mimicry as a mechanism for virus-induced autoimmunity. Immunol Res 1989; 8: 3-15. .
Google Scholar
 
 
8.
Oldstone MB. Molecular mimicry and immune-mediated diseases. FASEB J 1998; 12: 1255-1265. .
Google Scholar
 
 
9.
Samarkos M, Vaiopoulos G. The role of infections in the pathogenesis of autoimmnune diseases. Curr Drug Targets Inflamm Allergy 2005; 4: 99-103. .
Google Scholar
 
 
10.
Ospelt C, Gay S. TLRs and chronic inflammation. Int J Biochem Cell Biol 2009 Oct 17; [Epub ahead of print]. .
Google Scholar
 
 
11.
Pisetsky DS. The role of innate immunity in the induction of autoimmunity. Autoimmun Rev 2008; 8: 69-72. .
Google Scholar
 
 
12.
Oukka M. Th17 cells in immunity and autoimmunity. Ann Rheum Dis 2008; 67 (Suppl III): 26-29. .
Google Scholar
 
 
13.
Koutouzov S, Mathian A, Dalloul A. Type-I interferons and systemic lupus erythematosus. Autoimmun Rev 2006; 5: 554-562. .
Google Scholar
 
 
14.
Gottenberg JE, Cagnard N, Lucchesi C, et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci USA 2006; 103: 2770-2775. .
Google Scholar
 
 
15.
Walsh RJ, Kong SW, Yao Y, et al. Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis. Arthritis Rheum 2007; 56: 3784-3792. .
Google Scholar
 
 
16.
Friedman I, Laufer A, Ron N, et al. Experimental myocarditis: in vitro and in vivo studies of lymphocytes sensitized to heart extracts and group A streptococci. Immunology 1971; 20: 225-232. .
Google Scholar
 
 
17.
Cunningham MW, McCormack JM, Talaber LR, et al. Human monoclonal antibodies reactive with antigens of the group A Streptococcus and human heart. J Immunol 1988; 141: 2760-2766. .
Google Scholar
 
 
18.
Adderson EE, Shikhman AR, Ward KE, et al. Molecular analysis of polyreactive monoclonal antibodies from rheumatic carditis: human anti-N-acetylglucosamine/anti-myosin antibody V region genes. J Immunol 1998; 161: 2020-2231. .
Google Scholar
 
 
19.
Mertens NM, Galvin JE, Adderson EE, et al. Molecular analysis of cross-reactive anti-myosin/anti-streptococcal mouse monoclonal antibodies. Mol Immunol 2000; 37: 901-913. .
Google Scholar
 
 
20.
Cunningham MW, McCormack JM, Fenderson PG, et al. Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence GLN-LYS-SER-LYS-GLN in M protein. J Immunol 1989; 143: 2677-2683. .
Google Scholar
 
 
21.
Bronze MS, Dale JB. Epitopes of streptococcal M proteins that evoke antibodies that cross-react with human brain. J Immunol 1993; 151: 2820-2828. .
Google Scholar
 
 
22.
Kalish RA, Leong JM, Steere AC. Early and late antibody responses to full- length and truncated constructs of outer surface protein A of Borrrelia burgdorferi in Lyme disease. Infect Immun 1995; 63: 2228-2235. .
Google Scholar
 
 
23.
Szechiński J. Borelioza. W: Reumatologia kliniczna. Tom 2. Zimmermann-Górska I. (red.). Wyd. Lek. PZWL, Warszawa 2008; 799-804. .
Google Scholar
 
 
24.
Unterman A, Shoenfeld Y, Chapman J. Guillain-Barré and other immune-mediated neuropathies. In: Diagnostic Criteria in Autoimmune Diseases. Shoenfeld Y, Cervera R, Gershwin ME (ed.). Humana Press 2008; 427-432. .
Google Scholar
 
 
25.
Aspinall GO, Fujimoto S, McDonald AG, et al. Lipopolisaccharides from Campylobacter jejuni associated with Guillain-Barré syndrome patients mimic human gangliosides in structure. Infect Immun 1994; 62: 2122-2125. .
Google Scholar
 
 
26.
Koga M, Yuki N. Campylobacter jejuni cst-II polymorphisms and association with development of Guillain-Barré syndrome. Neurology 2007; 69: 1727-1728. .
Google Scholar
 
 
27.
Lasky T, Terracciano GJ, Magder L, et al. The Guillain-Barré syndrome and the 1992-1993 and 1993-1994 influenza vaccines. N Engl J Med 1998; 339: 1797-1802. .
Google Scholar
 
 
28.
Bertolaccini ML, Hughes GRV, Khamashta MA. Systemic lupus erythematosus. In: Diagnostic Criteria in Autoimmune Diseases. Shoenfeld Y, Cervera R, Gershwin ME (ed.). Humana Press 2008; 3-8. .
Google Scholar
 
 
29.
Tsai YT, Chiang BL, Kao YF, et al. Detection of Epstein-Barr virus and cytomegalovirus genome in white blood cells from patients with juvenile rheumatoid arthritis and childhood systemic lupus erythematosus. Int Arch Allergy Immunol 1995; 106: 235-240. .
Google Scholar
 
 
30.
Kang I, Quan T, Nolasco H, et al. Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J Immunol 2004; 172: 1287-1294. .
Google Scholar
 
 
31.
Zandman-Goddard G, Berkun Y, Barzilai O, et al. Exposure to Epstein-Barr virus infection is associated with mild systemic lupus erythematosus disease. Ann N Y Acad Sci 2009; 1173: 658-663. .
Google Scholar
 
 
32.
Medzhitov R. Toll-like receptors and innate immunity. Nature Rev Immunol 2001; 1: 135-145. .
Google Scholar
 
 
33.
Gross AJ, Hochberg D, Rand WM, et al. EBV and systemic lupus erythematosus: a new perspective. J Immunol 2005; 174: 6599-6607. .
Google Scholar
 
 
34.
Strachan DP. Hay fever, hygiene, and household size. Br Med J 1989; 299: 1259-1260. .
Google Scholar
 
 
35.
Bodansky HJ, Staines A, Stephenson C, et al. Evidence for an environmental effect in the aetiology of insulin dependent diabetes in a transmigratory population. Br Med J 1992; 304: 1020-1022. .
Google Scholar
 
 
36.
Ram M, Anaya JM, Barzilai O, et al. The putative protective role of hepatitis B virus (HBV) infection from autoimmune disorders. Autoimmun Rev 2008; 7: 621-625. .
Google Scholar
 
 
37.
Krause I, Anaya JM, Fraser A, et al. Anti-infectious antibodies and autoimmune-associated autoantibodies in patients with type I diabetes mellitus and their close family members. Ann N Y Acad Sci 2009; 1173: 633-639. .
Google Scholar
 
 
38.
King C, Ilic A, Koelsch K, et al. Homeostatic expansion of T cells Turing immune insufficiency generates autoimmunity. Cell 2004; 117: 265-277. .
Google Scholar
 
 
39.
Alyanakian MA, Grela F, Aumenieur A, et al. TGF-beta and NKT cells are involved In the protective effect of a bacterial extract on type 1 diabetes. Diabetes 2006; 55: 179-185. .
Google Scholar
 
 
40.
Lang KS, Recher M, Junt T, et al. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat Med 2005; 111: 138-145. .
Google Scholar
 
 
41.
Quintana FJ, Rotem A, Carmi P, et al. Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity. J Immunol 2000; 165: 6148-6155. .
Google Scholar
 
 
42.
Conti F, Rezai S, Valesini G. Vaccination and autoimmune rheumatic diseases. Autoimmun Rev 2008; 8: 124-128. .
Google Scholar
 
 
43.
Shoenfeld Y, Aharon-Maor A, Sherer Y. Vaccination as an additional player in the mosaic of autoimmunity. Clin Exp Rheumatol 2000; 18: 181-184. .
Google Scholar
 
 
44.
Nocton JJ, Bloom BJ, Rutledge BJ, et al. Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis. N Engl J Med 1994; 330: 229-234. .
Google Scholar
 
 
45.
Sigal LH. Lyme disease; a review of aspects of its immunology and immunopathogenesis. Ann Rev Immunol 1997; 15: 63-92. .
Google Scholar
 
 
46.
Sriram S, Stratton CW, Yao S, et al. Chlamydia pneumoniae infection of the central nervous system in multiple sclerosis. Ann Neurol 1999; 46: 6-14. .
Google Scholar
 
 
47.
Mori M, Kuwabara S, Miyake M, et al. Hemophilus influenzae infection and Guillain-Barré syndrome. Brain 2000; 123: 2171-2178. .
Google Scholar
 
 
48.
Kusunoki S, Shiina M, Kanazawa I. Anti-Gal-C antibodies in GBS subsequent to mycoplasma infection: evidence of molecular mimicry. Neurology 2001; 57: 736-738. .
Google Scholar
 
 
49.
Fenderson PG, Fischetti VA, Cunningham MW. Tropomyosin shares immunologic epitopes with group A streptococcal M proteins. J Immunol 1989; 142: 2475-2481. .
Google Scholar
 
 
50.
Snider LA, Swedo SE. Post-streptococcal autoimmune disorders of the central nervous system. Curr Opin Neurol 2003; 16: 359-365. .
Google Scholar
 
 
51.
Kurlan R. Tourette's syndrome and 'PANDAS': will the relation bear out? Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection. Neurology 1998; 50: 1530-1534. .
Google Scholar
 
 
52.
Cunha-Neto E, Dzau VJ, Allen PD, et al. Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. Am J Pathol 2005; 167: 305-313. .
Google Scholar
 
 
53.
Lundberg P, Welander P, Han X, et al. Herpes simplex virus type 1 DNA is immunostimulatory in vitro and in vivo. J Virol 2003; 77: 11158-11169. .
Google Scholar
 
 
54.
Barzilai O, Sherer Y, Ram M, et al. Epstein-Barr virus and cytomegalovirus in autoimmune diseases: are they truly notorious? A preliminary report. Ann N Y Acad Sci 2007; 1108: 567-577. .
Google Scholar
 
 
55.
Toussirot E, Roudier J. Epstein-Barr virus in autoimmune diseases. Best Pract Res Clin Reumatol 2008; 22: 883-896. .
Google Scholar
 
 
56.
Jun HS, Yoon JW. A new look at viruses in type 1 diabetes. Diabetes Metab Res Rev 2003; 19: 8-31. .
Google Scholar
 
 
57.
Tam PE. Coxsackievirus myocarditis: interplay between virus and host in the pathogenesis of heart disease. Viral Immunol 2006; 19: 133-146. .
Google Scholar
 
 
58.
Pak Y, Eun HM, McArthur RG, et al. Association of cytomegalovirus infection with autoimmune type 1 diabetes. Lancet 1988; 2: 1-4. .
Google Scholar
 
 
59.
Labarca JA, Rabaggliati RM, Radrigan FJ, et al. Antiphospholipid syndrome associated with cytomegalovirus infection: case report and review. Clin Infect Dis 1997; 24: 197-200. .
Google Scholar
 
 
60.
Agmon-Levin N, Ram M, Barzilai O, et al. Prevalence of hepatitis C serum antibody in autoimmune diseases. J Autoimmun 2009; 32: 261-266. .
Google Scholar
 
 
61.
Antonelli, Ferri C, Ferrari SM, et al. Immunopathogenesis of HCV-related endocrine manifestation in chronic hepatitis and mixed cryoglobulinemia. Autoimmune Rev 2008; 8: 18-23.
Google Scholar
 
 
Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Udostępnij
Wyślij mailem
ARTYKUŁ POWIĄZANY
Echokardiografia dla reumatologów: choroby autoimmunologiczne
Zastosowanie dożylnych preparatów immunoglobulin u dzieci z chorobami reumatycznymi
Odmienności chorób autoimmunologicznych i autoinflamatoryjnych – znaczenie dla praktyki klinicznej reumatologa
Autoimmunologiczny/autozapalny zespół indukowany przez adiuwanty – nowy problem diagnostyczny czy rozwiązanie zagadki diagnostycznej
Skostnienia okołostawowe po dwuetapowym leczeniu infekcji endoprotezy stawu kolanowego u chorej na reumatoidalne zapalenie stawów
Indeksy
 
Indeks słów kluczowych
Indeks dziedzin
Indeks autorów
eISSN:2084-9834
ISSN:0034-6233
Journals System - logo
© 2006-2024 Journal hosting platform by Bentus
Scroll to top